Leptospirosis, Focus on Related Acute Kidney Injury among Albania Patients

Abstract: The aim: Describing hospital epidemiological finding, clinical, laboratory results and outcome focus on renal complications of the patients diagnosed with leptospirosis.. Background: Leptospirosis is a zoonosis caused by spirochete genus Leptospira. Its clinical symptoms range from mild, self-limited disease to life threatening complications such as acute kidney injury, liver failure and bleeding. Materials and methods: 119 consecutive patients enrolled in the study from 2010-2015. They were admitted at Infection Diseases Department and Nephrology Department of U.H.C: Mother Teresa” in Tirana. Data are collected retrospectively from patient charts. Statistical analysis was performed using Medcalc 14.8.1 and IBM SPSS 20. Leptospirosis infection was detected by enzyme-linked immunosorbent assay (ELISA). Results: There was a total of 119 patients diagnosed with the condition from 2010-2015. 8% were female, 92% male. Age ranged from 15 to 78, mean 48.2 ± 15.4. 51 % developed AKIN III, 48 % F stage according to RIFLE. Mean length of stay was 14.1±7.4 days. Mortality was 8.4 % (10 patients) in our cohort. The number of cases peaked in June through the study years. Conclusion: Leptospirosis is a zoonosis with a clinical picture ranging from mild to severe. Severe cases are associated with high mortality in the Albanian population. AKI is a frequent complication of leptospirosis in our study cohort. Multidisciplinary approach and timely intervention may help prevent complications and reduce mortality. Keywords: leptospirosis, AKI, Albania. Title: Leptospirosis, Focus on Related Acute Kidney Injury among Albania Patients Author: Rista Elvana, Pilaca Arben, Akshija Ilir, Harxhi Arian, Harja Endri, Kraja Dhimiter, Puca Edmond, Dyrmishi Blertina, Cadri Vilma, Duraku Ahmet, Thereska Nestor International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

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