Abstract: Myocardial infarction (MI) remains a leading cause of morbidity and death regardless of targeting of low-density lipoprotein (LDL) cholesterol by statin treatment. The requirement for recognition of extra causal factors. We aimed by this comprehensive review to discuss the role of lipoprotein (A) as a risk factor of the most devastating ischemic heart disease which is myocardial infarction. We Conducted a database; PubMed and Embase comprehensive search up to December 2016, we search a relevant trail to our concern topic (Role of Lipoprotein (a) as risk factor of cardiovascular diseases, myocardial infarction). The occurrence of elevated serum Lp(a) level was not significantly different in between patients with myocardial infarction and control subjects, recommending that this lipoprotein might not play a crucial role in the pathogenesis of ischemic heart diseases. Numerous studie showed a significantly greater level of serum Lp(a) was noted in patients with, than in those without, prior MI, recommending that Lp(a) is a risk factor for the occurrence of AMI. Raised Lp(a) levels might promote atherosclerosis via Lp(a)-obtained cholesterol entrapment in the intima, through inflammatory cell recruitment, and/or by means of the binding of pro-inflammatory-oxidized phospholipids.
Keywords: Myocardial infarction (MI), low-density lipoprotein (LDL).
Title: Lipoprotein (A) As a Risk Factor in Myocardial Infarction
Author: Torki Mosaad Ahmed, Shaker Hassan S Aljabri, Baraa Emad Abuzinadah, Abdullah Abbas Mohamed
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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