Abstract: a new reversed phase simple, economic and specific validated high-performance liquid chromatography method for estimation of Empagliflozin in human plasma. Mobile phase used is methanol: acetonitrile (50:50% v/v). uv detection at 225nm.the bioanalytical procedure involves deproteination of plasma with liquid-liquid extraction. The percentage of relative recovery and coefficient of variation of accuracy and precision were within acceptable limits. The method proved in simple, cost-effective, and sensitive foe estimation of Empagliflozin in human plasma.
Keywords: Empagliflozin, liquid-liquid extraction, human plasma, method development, validation, bioanalytical procedure.
Title: Method development and validation for Estimation of Empagliflozin by UV spectrophotometry in human plasma
Author: Dr.K. Bhavyasri, M.V.S. Lavanya, Dr.D.Rambabu
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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