Monoclonal Antibodies in Chronic Rhinosinusitis with nasal polips (CRSwNP): our 12 months experience

F.Asprea, D. Bruzzese, D. Costanzo, G.Lucchesi, G.Micali

Abstract: Chronic rhinosinusitis (CRS) is a chronic inflammatory disease of the nasal and paranasal cavities. About 20% of chronic rhinosinusitis is represented by rhinosinusitis with nasal polyps (CRSwNP), which in most cases is caused by a type 2 inflammation, with an eosinophilic inflammation.

Monoclonal antibodies are a targeted therapy that allows you to control the disease by limiting or abolishing the use of systemic steroids.

In this scientific work, the authors tested the efficacy of mepolizumab and dupilumab in patients with nasosinusal polyposis with a 12-month follow-up.

Keywords: Chronic Rhinosinositis, nasal polyps, monoclonal antibodies, mepolizumab, dupilimab.

Title: Monoclonal Antibodies in Chronic Rhinosinusitis with nasal polips (CRSwNP): our 12 months experience

Author: F.Asprea, D. Bruzzese, D. Costanzo, G.Lucchesi, G.Micali

International Journal of Healthcare Sciences

ISSN 2348-5728 (Online)

Vol. 10, Issue 2, October 2022 - March 2023

Page No: 181-186

Research Publish Journals

Website: www.researchpublish.com

Published Date: 17-January-2023

DOI: https://doi.org/10.5281/zenodo.7543657

Vol. 10, Issue 2, October 2022 - March 2023

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Monoclonal Antibodies in Chronic Rhinosinusitis with nasal polips (CRSwNP): our 12 months experience by F.Asprea, D. Bruzzese, D. Costanzo, G.Lucchesi, G.Micali