Abstract: Nephrotic syndrome is a condition of massive proteinuria (protein leaks from the blood to the urine through the glomeruli) that leads to hypoalbuminaemia and oedema. There are many specific causes of nephrotic syndrome. Nephrotic syndrome may affect adults and children, of both sexes and of any race. It may occur in typical form, or in association with nephritic syndrome. Objective: the propose of this study is to review and analysis previous based evidence studies that concerns with the classification, pathogensis, Etiology, , diagnosis and treatment outcomes of nephrotic syndrome, including all population of different ages and both sex. Methodology: we conducted systemic review with meta-analysis search through medical database online such as Medline; we include all those studies which were published in the last 15 years (2000-2015) about nephrotic syndrome. Conclusion: Patients with nephrotic syndrome can present to primary or secondary care with diverse symptoms that reflect the primary process or with one of the many systemic complications of the syndrome. For patients with nephrotic syndrome attributable to treatment-resistant glomerulonephritis, some benefits may be obtained with the new immunosuppressive drugs used in organ transplantation, such as cyclosporine, mycophenolate mofetil, and in some cases tacrolimus. For patients with diabetes mellitus or amyloidosis and for some patients with glomerulonephritis that does not respond to any immunosuppressive treatment, no causal treatment is currently possible.
Keywords: Nephrotic syndrome, adults and children, both sexes, cyclosporine.
Title: Nephrotic Syndrome
Author: Ibrahim Abdullak Alqurashi, Mohammad Jaman Althaqafi, Faris Ahmed Althomali, Abdulaziz Ahmed Alzaher
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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