Abstract: Aim of this review was to evaluate the updated evidence on the treatment of acute liver failure (ALF), and moreover to discuss the diagnosis approaches which will determine the optimal treatment for ALF. We review the most updated studies in the management approaches of acute liver failure, but we also included some studies which are published earlier than 1995 December, up to December 2016 the Midline (PubMed) and Embase databases were searched for relevant articles to our concern subject, and then evidence was extracted carful from each study, to be able to performed this review as an updated study for all treatment approaches of ALF. Severe liver failure can be associated with rapidly progressive multiorgan failure and devastating issues; however, outcomes have actually been improved by use of emergency situation liver transplantation. A proof base for practice is emerging for supportive care, and a better understanding of the pathophysiology of the condition, specifically in relation to hepatic encephalopathy, will probably soon cause further enhancements in survival rates. Other evidence stated that Liver transplant remains the only intervention with survival benefit. Liver assist gadgets and hepatocyte transplant stay experimental and more advances are required. Public health measures to control hepatitis A, B, E, and drug-induced liver injury will lower the occurrence and death of ALF.
Keywords: Acute Liver Failure (ALF), Public health measures.
Title: Optimal Treatment of Acute Liver Failure in Adults (ALF): Overview
Author: Abdulsalm rashed alshehri, Layth Khalid Alsulaiman, Abdullah Juayf Alanazi, Abdullah Saleh Alghanmi, Yasir Hameed Albeladi, Mugbil saad saeed Aljaman, Waheed Ali Ahmad Alshehri
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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