Abstract: Chronic osteomyelitis, or bone infection, is a major worldwide cause of morbidity and mortality, as it is exceptionally hard to treat due to patient and pathogen-associated factors. The pathophysiology of chronic osteomyelitis is multifactorial and starts with spread of microscopic organisms. Microscopic organisms might achieve the bone by hematogenous seeding, direct immunization, or airborne sullying. The effective use of local antibiotic treatment of osteomyelitis requires a detailed understanding of the characteristics and pathophysiology of this disease. The most common pathogens responsible for osteomyelitis in humans are Staphylococcus species, followed by Enterobacteriaceae and Pseudomonas species.
Objective: the aim of this paper is to review the complication and outcomes of antibiotics treatment of osteomyelitis, based on evidence of previous studies.
Methodology: we conducted systemic search through several databases mostly Midline (pubmed) up to 2015, and we have included all those studies that discussed the treatment of osteomyelitis, and we finally exclude some of studies based on their validity in this field, then we finally analysis the different outcomes of antibiotics methods treatments, and their complications, from each study that were included.
Results: An antibiotic is generally begun at the earliest opportunity. The introductory antibiotic picked is one that is prone to murder the germs (microscopic organisms) which regularly cause osteomyelitis. Be that as it may, the antibiotic is here and there changed to an alternate one when the aftereffects of the tests affirm which bacterium is bringing about the contamination. So the complication depending missing the right antibiotic for the right type of bacteria that is causing OM.
Conclusion: Acute hematogenous osteomyelitis is typically requires a much shorter course of antibiotic therapy than in chronic osteomyelitis in adults. And usually the short term therapy has better outcome and less complication adverse.
Keywords: Antibiotics Treatment, Outcomes and Complications, Acute hematogenous osteomyelitis.
Title: Outcomes and Complications of Antibiotics Treatment of Osteomyelitis
Author: Majed mohammed albaqami, Mohammad Abdullah Albogami, Rami abdullah alsuwat, Ahmed Eidhah Aloufi
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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