Overview of Diagnosis and Treatment Approaches of Gastroparesis

Hassan Awad Al-Raba'ie, Osamah Abdulaziz Ali Alsalmh, Turki Mohammad Abdullah Alshehri, Abdulrahman Mubarak Alahmari, Ahmed Mohammed Awadh AL-Antar, Faisal Abdullah Hassan Alshehri, Mohammad Hassan AlShehri

Abstract: Gastroparesis (GP) is a chronic neuromuscular disorder of the upper intestinal tract, likewise called delayed gastric emptying, which is a motility condition of the stomach that is identified by slowed emptying of food in the absence of mechanical obstruction. The objective of this study was to review the evidence of diagnosis and treatment of Gastroparesis (GP) in general, we intended to demonstrate the different diagnostic procedures used in this manner, and to overview the impact of this disorder in internal care unit of GI. Systematic detailed search was conducted through several databases including; PubMed/MIDLINE, Google scholar, and Embase, searching the literature for relevant studies discussing the Gastroparesis (GP) and especially those articles concerning diagnosis and treatment of GP. Then for more evidence the references of each article was manually searched for more relevant studies to be included in our review, English language restriction was applied in this current search, and with only human subject’s articles. Clinical features and underlying diseases may suggest the existence of gastroparesis. Gastric discommendation or accelerated gastric emptying might result in dyspeptic symptoms such as early satiety, nausea, and bloating, which may suggest gastroparesis, and, thus, formal measurement of gastric emptying is key before beginning therapy whenever this kind of test is offered. Several tests consisting of gastric emptying scintigraphy and stable isotope breath tests are available for the assessment of patients with believed gastroparesis. New prokinetic agents that seem much safer and to preserve efficacy may be offered in the next couple of years. Endoscopic venting and feeding tubes placed in accordance with signs and dietary requirements lead to decreased need for hospitalization in patients with refractory gastroparesis. Keywords: Gastroparesis (GP), chronic neuromuscular disorder. Title: Overview of Diagnosis and Treatment Approaches of Gastroparesis Author: Hassan Awad Al-Raba'ie, Osamah Abdulaziz Ali Alsalmh, Turki Mohammad Abdullah Alshehri, Abdulrahman Mubarak Alahmari, Ahmed Mohammed Awadh AL-Antar, Faisal Abdullah Hassan Alshehri, Mohammad Hassan AlShehri International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Vol. 4, Issue 2, October 2016 – March 2017

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Overview of Diagnosis and Treatment Approaches of Gastroparesis by Hassan Awad Al-Raba'ie, Osamah Abdulaziz Ali Alsalmh, Turki Mohammad Abdullah Alshehri, Abdulrahman Mubarak Alahmari, Ahmed Mohammed Awadh AL-Antar, Faisal Abdullah Hassan Alshehri, Mohammad Hassan AlShehri