Overview of Malignant Melanoma and Treatment Approaches

Abstract: Melanoma is a serious form of skin cancer it is a disease in which malignant (cancer) cells form melanocytes (cells that color the skin). This review was aimed to overview the malignant melanoma from different perspectives, we intended to discuss the bases and etiology behind melanoma forming, but the main aim was to evaluate the treatment options of malignant melanoma. An electronic database (PubMed/Midline, and Embase) were comprehensively searched for relevant articles there were published in English language and containing human subjects only up to December 2016. we used a following term as Mesh term to find related trails to our study; “malignant melanoma” Or ‘skin cancer” Or” metastatic melanoma” combined with “management” Or “treatment approaches”, Moreover we searched the references of each identified study for more related articles to support our evidence on treatment approaches of malignant melanoma. Treatment of melanoma malignancy remains an obstacle. Identifying the mutations in the various paths that cancer malignancy patients have obtained would enable the ongoing advancement of more efficacious treatments that aim to prevent drug resistance and cancer recurrence. The convergence of immunology with other disciplines of biomedical research would lead to additional improvement in the advancement of more recent and more efficacious restorative approaches to manage this debilitating and fatal disease While surgical treatment and radiation therapy might play a role in the palliation of signs from local tumor growth, systemic treatment is the essential of treatment for metastatic cancer malignancy. Keywords: malignant (cancer) cells, Treatment Approaches. Title: Overview of Malignant Melanoma and Treatment Approaches Author: Mohammed Talal Abdulhameed Alghamdi, Mohamed Sayed Yousef, Alwaleed Fahad Altemani, Doaa Khalid Bajabir, Mohammed Ali Mohammed Alasmari, Abdulhamid Talal Abdulhamid Alghamdi, Alruwhithi Ziad Abdulmoti, Yazeed Fahad Altemani, Abdullah Abdulaziz Alshehri, Emran Abbas A Khojah, Meshari Saleem M Alwagdani, Mohammad Siraj Ahmad, Hannin Mohammed Al reqei International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

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