Overview of Multiple Myeloma, Risk Factors, Treatment Approaches

Zuhair Alhasan Jabour, Mohammed Omar Mohammed Alsayed, Hassan Mohammad Homadi, Mohammed Abdullah Eidoh, Mohammad Abdullah Mohammad Alkhallaf, Mariam Mohammed Hassan Ayashi, Sanhan salman Jaber al-malki, Ahmad Saeed Mohammad Alayed, Manar Mohammad Dabi

Abstract: The main goal of this review paper was to overview the Multiple myeloma (MM) in many clinical aspects, and mainly discussing the risk factors, and more importantly the treatment approaches toward this type of malignant bone marrow cancer. We conducted a comprehensive review through the literature using electronic databases; Medline, PubMed and Embase. Eligible studies were sought in PubMed with language restriction to English articles and with human subjects only; search was over these studies published up to January, 2017. Several myeloma (MM) is defined by the neoplastic spreading of a solitary clone of plasma cells generating a monoclonal immunoglobulin. The initial step in coming close to a possible brand-new patient with MM is to verify the diagnosis given that the premalignant phases of myeloma, specifically monoclonal gammopathy of undetermined importance (MGUS) as well as smoldering numerous myeloma (SMM), do not require treatment and may be easily misdiagnosed as MM The therapy of myeloma relies on whether the patient has smoldering myeloma or symptomatic myeloma. Patients with smoldering myeloma are generally observed, with treatment initiated after disease progression to energetic MM. There is no evidence that early therapy of asymptomatic myeloma extends total survival. Patients with symptomatic, energetic myeloma require treatment. This treatment is patient-specific and relies on numerous factors including age, comorbidities, and performance condition. Keywords: Multiple myeloma (MM), risk factors, disease progression, therapy, symptomatic, treatment. Title: Overview of Multiple Myeloma, Risk Factors, Treatment Approaches Author: Zuhair Alhasan Jabour, Mohammed Omar Mohammed Alsayed, Hassan Mohammad Homadi, Mohammed Abdullah Eidoh, Mohammad Abdullah Mohammad Alkhallaf, Mariam Mohammed Hassan Ayashi, Sanhan salman Jaber al-malki, Ahmad Saeed Mohammad Alayed, Manar Mohammad Dabi, Waleed Hassan Ahmed Al Abdulhadi, Mohammed Awadh Masoud ALQahtani, Ali Omar Moftah International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Vol. 4, Issue 2, October 2016 – March 2017

Citation
Share : Facebook Twitter Linked In

Citation
Overview of Multiple Myeloma, Risk Factors, Treatment Approaches by Zuhair Alhasan Jabour, Mohammed Omar Mohammed Alsayed, Hassan Mohammad Homadi, Mohammed Abdullah Eidoh, Mohammad Abdullah Mohammad Alkhallaf, Mariam Mohammed Hassan Ayashi, Sanhan salman Jaber al-malki, Ahmad Saeed Mohammad Alayed, Manar Mohammad Dabi