Overview of Peptic Ulcer Disease, Etiology, Diagnosis and Treatment

Abstract: This review study was aimed to discuss the Peptic ulcer disease (PUD) from different aspects, mostly will try to emphasizes the risk factors associated with PUD, and also pathogenesis, in Addition to aid the diagnostic approaches, and finally the treatment options for PUD. A comprehensive detailed search was conducted to identify literature discussing Peptic ulcer disease (PUD) general population, published up to November 2016. Searching was conducted through; PubMed, EMBASE and the Cochrane library databases, were searched for studies of human subjects only. Furthermore, references found in identified articles were manually searched for more relevant studies to be included in this review. Peptic ulcer disease is an issue of the gastrointestinal tract defined by mucosal damage secondary to pepsin and gastric acid secretion. It normally happens in the stomach and proximal duodenum; less frequently, it occurs in the lower esophagus, the distal duodenum, or the jejunum. Testing for and eliminating H. pylori infection in patients is suggested prior to starting NSAID treatment, and for those currently taking NSAIDs, when there is a history of ulcers or ulcer complications. Comprehending the pathophysiology and best treatment strategies for non-NSAID, non-H. pylori-associated peptic ulcers presents a challenge. Keywords: Peptic ulcer disease (PUD), diagnosis and treatment. Title: Overview of Peptic Ulcer Disease, Etiology, Diagnosis and Treatment Author: Azhar Eisa Dallak, Rafan Abdulrhman Madkor, Albaraa Mohammad Madkhali, Manal Ibrahim Bahkali, Tayseer Hasan Hakami, Abadi Abdullah Hakami, Rbouah Mohammad Ayashi, Abdullatif Alhassan Fathi, Sawsan Mohammed Abu Hadi, Ebtehal Zaid Alqahtani, Ali Khudaysh Muqri, Omar Abdulaziz Madkhali International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

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