Pancytopenia with Hyperthyroidism

Dr. Moosa Jeded S Alenazi

Abstract: Pancytopenia is a rare complication of hyperthyroidism. Several cases had been reported before in the literature, the pathogenesis is still unclear. Immunological mechanisms have been suggested to be involved in the reduction of the life-span of blood cells and platelets. Hyperthyroidism can be associated with various hematological disorders, Especially single lineage abnormalities such as anemia (34%), leukopenia (5.8%), thrombocytopenia (3.3%) are reported, but pancytopenia is a rare presentation of hyperthyroidism. The suspected etiologic mechanisms include ineffective hematopoiesis, reduction in blood cell life span, autoimmune process, toxicity of thyroid hormone. We report a case describes a 47 yr old, female with pancytopenia. On further investigations the patient was found to have hyperthyroidism. Keywords: Pancytopenia, Hyperthyroidism, thyrotoxicosis, hematopoiesis. Title: Pancytopenia with Hyperthyroidism Author: Dr. Moosa Jeded S Alenazi International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Vol. 4, Issue 2, October 2016 – March 2017

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Pancytopenia with Hyperthyroidism by Dr. Moosa Jeded S Alenazi