Abstract: Polycystic kidney disease (PKD) is a group of monogenic disorders that result in renal cyst development. Our aim to discuss the types of PKD, their pathophysiology, to outline diagnosis and possible complications Our search strategies were performed using biomedical databases; Medline, and Embase, for studies concerned with Polycystic kidney disease (PKD) published with English language up to, October 2017. PKD is an inherited condition defined by cystic expansion of the kidneys generating progressive kidney enhancement and also kidney insufficiency, along with different extrarenal manifestations. PKD is associated with major hepatointestinal complications. The progression of acute pancreatitis and peptic ulcer bleeding had a negative effect on general death in patients with PKD. For that reason, acute pancreatitis and cholangitis need to be listed in the differential medical diagnosis of acute abdominal pain in patients with PKD. For anemia survey in patients with PKD, peptic ulcer bleeding must be taken into consideration.
Keywords: pathophysiology, Polycystic kidney disease, diagnosis, patients.
Title: Pathophysiology, Etiology, and Complications of Polycystic Kidney Disease
Author: Mohammad khalid halabi, Atrab Yousof Hawalah, Banan matuq aloufi, Abdulkareem Abdullah Alharthi, Rahaf Matoug Alofi, Amr Zuhier Badawi, Yazid abdulrahman Alhadlg, Bader Abdulrahman Alageel, Hisham muhammedeed Almuallim, Abdulsalam S. Alluhaydan
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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