POTENTIAL OF BROCCOLI (Brassica Oleracea L. Var italica) EXTRACT AGAINST THE REDUCTION OF MDA LEVELS IN DIABETES MELLITUS TYPE II

Fadilla Ummaiya, Widya Hardianti, Dyta Putri Aryo, Elvina Veronica, I Wayan Sugiritama

Abstract: Diabetes Mellitus (DM) is a metabolic disease characterized by chronic hyperglycemia and accompanied by various metabolic disorders due to abnormal insulin secretion.  Around 90% of DM cases in the world are type 2 of DM and 80% of them are found in developing countries. Indonesia ranks seventh in the country with the most diabetes cases in the world. DM treatment usually expensives and has adverse effects so alternative treatments are needed which are relatively inexpensive, whose properties are not much different from synthetic drugs and are safe for consumption in the long term. Broccoli (Brassica oleracea L. var Italica) is a kind of vegetable that is easy to find and cultivate and contains lots of antioxidants and nutrients. The aim of knowing the potential of broccoli in reducing malondialdehyde (MDA) in patients with type 2 of DM. Methods: The study was derived from various relevant literatures in last 10 years using keywords. Literature from international journals and national journals accessed on PubMed, Garuda, NCBI, and Google Scholar. Results: Antioxidants in extract of broccoli are hepatoprotective and reduce MDA levels in type 2 of DM patients by inhibiting the initiation and propagation of free radical oxidation reactions. Conclusion: Broccoli’s extract has the potential to reduce MDA levels in patients with Type 2 of Diabetes Melitus.

Keywords: Broccoli, Malondialdehid, Diabetes Mellitus Type 2.

Title: POTENTIAL OF BROCCOLI (Brassica Oleracea L. Var italica) EXTRACT AGAINST THE REDUCTION OF MDA LEVELS IN DIABETES MELLITUS TYPE II

Author: Fadilla Ummaiya, Widya Hardianti, Dyta Putri Aryo, Elvina Veronica, I Wayan Sugiritama

International Journal of Healthcare Sciences

ISSN 2348-5728 (Online)

Research Publish Journals

Vol 8, Issue 2, October 2020 - March 2021

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POTENTIAL OF BROCCOLI (Brassica Oleracea L. Var italica) EXTRACT AGAINST THE REDUCTION OF MDA LEVELS IN DIABETES MELLITUS TYPE II by Fadilla Ummaiya, Widya Hardianti, Dyta Putri Aryo, Elvina Veronica, I Wayan Sugiritama