Abstract: Wound is a disruption of the anatomic structure and function in any body part. It includes burns, bone fracture, ulcers, skin break, muscle tear etc. The infection of a wound can be defined as the invasion of organism through tissues following a breakdown of local and systemic host defences leading to local and systemic presentation. Infection is also due to tissue infestation by microorganism with inflammation response. Antibiotics agents are the most as often as possible recommended medication for prevention of bacterial infection. Antibiotic are effective against various microorganism and the susceptibility to reduce adverse effect. Wound infections have a huge impact on patient quality of life. Rational use of antibiotics is important because the emergence of resistance has become a global threat. Antibiotics resistance is the ability of the microorganism to withstand the effect if any antibiotics, the microorganism changes in a way that reduces the effectiveness of the drug. Objective: To analyze the Prescribing pattern of antibiotics in wound infection and the resistance of microorganism in surgery department. Methodology: This was an observational study carried out over a period of 6 months among inpatient in the department of Surgery. The entire patient admitted in the Surgery ward meeting our inclusion criteria and exclusion criteria in this study were included. All the documented data were evaluated by applying appropriate statistical analysis like mean and standard deviation. Results: A total number of 130 patients was enrolled in our study performed in surgery department. From our study, the majority of study population were male (77.69%) and female were (22.30%).The high number of people belongs to group age of 56-65 years was 38 peoples. In wound infection, Diabetic foot (43.07%) was found to be a major problem followed by gangrene (28.84%) and cellulitis (12.31%).In our study, out of 130 cases, culture sensitivity test was performed for 95 cases and no culture sensitivity performed for 35 cases. Several samples such as Pus (53), wound swab (37) were collected. With reference to the culture sensitivity test, the major organisms isolated were categorized under gram negative such as E. Coli 22, Pseudomonas Aeruginosa 31. It can be observed that out of 130 patients included in our study 127 received antimicrobial therapy empirically while 3 patients did not received. Total of 18 different antibiotics were prescribed from which the most commonly prescribed were Metronidazole, Ceftriaxone and also the combination of ceftriaxone +metronidazole or Ceftriaxone + Metronidazole + Amikacin / Meropenem. Conclusion: The most antibiotics prescribed in the surgery department regarding wound infection were Metronidazole, Ceftriaxone and slightly Amikacin. The judicious use of antibiotic prophylaxis and reporting can be the most effective means to reduce the wound infection rate. Antimicrobial resistance in bacterial pathogens is a significant challenge that has a high morbidity and mortality.
Keywords: Wound infection, antimicrobial resistance, antibiotics agents, Ceftriaxone, Amikacin, Diabetic Foot.
Title: PRESCRIBING PATTERN OF ANTIBIOTICS IN WOUND INFECTION IN SURGERY DEPARTMENT
Author: Cla Gondo Dohanon Benedicte, Monica Chanchal, N’goran Hiwo Stephanie Laetitia, Salome Daniel Slahay, Dr.Raksha Yoganand, Dr.Divya Mol E.C
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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