Prevalence and Predictors of Amputation in Diabetic Foot Complications in Western Region of Saudi Arabia: A Retrospective Study

Basem AL Shareef, Mohammed Musfer Algamdi, Turki GhalebAlahmadi, Hatan Adnan Mohamad Khan, Muhanad Khalid Kondarji, Yazeed Fahad Altemani, Ayman Abdullah Alshehri, Rayan Tareq Jameel Alrefai

Abstract: Diabetes foot complication is a life time risk to the diabetes patients that increases the morbidity and mortality. Objective: To assess the prevalence and predictors of amputations among patients with diabetic foot complications followed up at a diabetic foot center (DFC), in Jeddah, Saudi Arabia. Methods: The current study was a retrospective analysis of diabetes patients registered at the DFC between Jan 2012 and Dec 2013, and were followed up for ≥ 3 month for diabetic foot ulcer. Data collected includes demographics, lifestyle, clinical factors, Wagner grade, accompanying clinical signs, associated factors (neuropathy, peripheral arterial disease [PAD], and foot trauma), management strategy, ulcer healing or amputation and mortality. Appropriate statistical tests were applied to identify the risk factors associated with amputation and binary logistic regression was used to analyze its predictors. Results: In total 147 diabetic patients, 73.5% males, mean age (SD) 53.90(16.43) years, mean (SD) duration of diabetes 11.33 (7.53) years, 57.8% had right foot ulcer, 32.2% had high Wagner grade (grade 4-5). Prevalence of amputation was observed in 40.1% (95%CI=32.6- 48.2). Predictors of amputation were age, low income or educational level, long diabetes duration, irregular follow-up, hypertension or visual impairment, existence of two or more comorbidities. Ulcer-related predictors were higher Wagner grade, associated neurovascular abnormalities, and infections. Conclusion: The current study suggests Wagner stage and association of co-morbidities as the major risk factors that predispose to amputation. Thus, enhance the need to recourse to specific therapeutic measures such as revascularization and surgical drainage. Keywords: Diabetic Foot, Complications, Ulcer, Gangrene, Amputation Title: Prevalence and Predictors of Amputation in Diabetic Foot Complications in Western Region of Saudi Arabia: A Retrospective Study Author: Basem AL Shareef, Mohammed Musfer Algamdi, Turki GhalebAlahmadi, Hatan Adnan Mohamad Khan, Muhanad Khalid Kondarji, Yazeed Fahad Altemani, Ayman Abdullah Alshehri, Rayan Tareq Jameel Alrefai International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Vol. 4, Issue 2, October 2016 – March 2017

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Prevalence and Predictors of Amputation in Diabetic Foot Complications in Western Region of Saudi Arabia: A Retrospective Study by Basem AL Shareef, Mohammed Musfer Algamdi, Turki GhalebAlahmadi, Hatan Adnan Mohamad Khan, Muhanad Khalid Kondarji, Yazeed Fahad Altemani, Ayman Abdullah Alshehri, Rayan Tareq Jameel Alrefai