Abstract: Transfusion-transmitted infections [Human immune deficiency virus (HIV), Hepatitis B virus (HBV), Hepatitis C virus (HCV), syphilis and malaria] acquired through the therapeutic blood transfusion process is a most important universal health problem in transfusion medicine. WHO, FDA and Indian government have selected mandatory testing criteria for each unit of blood in India. Design: Study was carried out over a period of 5 year i.e. 2009 to 2013. The conducted study was prospective and retrospective. The testing protocol was followed in the blood bank, after complete physical examination of blood donor by blood bank medical officer. Results: Over a five year period total blood donation was 10641, in which 9679 (90.39%) were replacement and remaining 962 (9.61%) were voluntary. There was a rise in number of voluntary donor over the five year period. The prevalence of HIV, HBsAg, HCV, Syphilis and Malaria was 11 (0.10%), 92 (0.86%), 129 (1.21%), 26 (0.24%) and 11 (0.10%) respectively. The seropositivity of HCV showed increasing trend from 2009 to 2013. The decreasing trends of prevalence were seen in HIV, Syphilis and Malaria. Conclusion: These findings propose that pre-donation counseling and donor self-exclusion will be effective in decreasing the TTI’s as well as practices of autologus blood transfusion should be encouraged. Nucleic acid amplification testing (NAT) must be implemented that identify blood donation made during the immunological window period before seroconversion.
Keywords: HIV-Human Immunodeficiency Virus, HBSAg-Hepatitis B Surface Antigen, HCV-Hepatitis C Virus, VDRL-Vineral Disease research Laboratory, WHO-World Health Organization.
Title: Prevalence of Transfusion Transmitted Infection among Blood Donors in Tertiary Care Hospital
Author: Yogesh Kumar. Monika Garg, Sushant Kumar Meinia
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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