Abstract: TTIs can be rooted by microorganisms which may be present in the blood or blood component. The major worldwide prevalent TTIs are caused by HIV, HBV, HCV, Treponema pallidum and malaria. The popular of the problems are due to the prevalence of asymptomatic carriers in the public and under window episode of infections. The WHO and National Blood Policy of India recommend that National Blood Services should be based on voluntary, non-remunerated blood donation. Laws related to blood transfusion in India are a part of the Drugs and Cosmetics Act 1945 (D&C Act). Every collected unit mandatorily tested for five major TTIs. With every unit of blood transfusion there is 1% chance of transfusion associated problems including transfusion-transmitted diseases. Design: This retrospective study was carried out over a period of 5 year i.e. 2011 to 2015. The testing protocol was followed in the blood bank, after complete physical examination of blood donor by blood bank medical officer. Results: Over a five year period total blood donation was 33507, in which 30184 (90%) were voluntary and remaining 3323 (10%) were replacement. This was due organized the blood donation camp time to time. The prevalence of HIV, HBsAg, HCV, Syphilis and Malaria was 52 (0.15%), 404 (1.20%), 396 (1.18%) and 04 (0.01%) respectively. The seropositivity of HBV was decreased every year continuously, whereas HIV, HCV and syphilis remain similar. The overall prevalence of the five year retrospective study (2011-2015) was 2.55%. Conclusion: Nucleic acid amplification testing (NAT) must be applied that identify blood donation made during the immunological window period before seroconversion. Information to TTIs reactive donor be a best method for prevent the chance of repeat reactive donation. Donor self-exclusion and encourage about the autologus blood transfusion will be effective in decreasing the TTI’s as well as practices of autologus blood transfusion should be encouraged.
Keywords: HIV, HBsAg, HCV, VDRL, North India, TTI.
Title: Prevalence of Transfusion Transmitted Infections among Blood Donors at Regional Blood Bank in north India
Author: Yogesh Kumar, Dr. Rajeev Panwar, Aarti Sharma
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
Research Publish Journals
