Abstract: Platelets indices have been recently reported as clinically useful biomarkers. In most clinical laboratories in Sudan; platelet indices are not reported/or evaluated, this could be of lack of knowledge about their availability, importance, and local laboratory reference values. The study aimed to determine the Sudanese reference value for platelet count and indices, to investigate whether a significant age/gender difference are exists. A total of 300 apparently healthy Sudanese; 150 males and 150 females, their ages range between 10 and 60 years; categorized in 5 groups. A full blood count was performed using Sysmex KX-21 blood analyzer and the platelet count and indices were recorded. The following reference values were obtained for platelet count – males 130-357x103 /µl , females 146-378 x103/µl; mean platelets volume (MPV) – males 8.4-11.4 fl, females 8.0-11.6 fl; platelets distribution width (PDW) – males 8.7-15.7 fl, females 7.8-16.2 fl; platelets -large cell ratio (P-LCR) – males 12.7-36.1%, females 10.9-38.8%; plateletcrit (PCT)–males 0.14-0.24%, females 0.13-0.33%. A significant difference between males/females and ages below/over 35 years were obtained for platelet count (p: 0.0001, 0.0001) and PCT (p: < 0.0001, 0.0006); respectively, while other indices did not show significant differences. This study illustrated the importance of determining local reference values, because populations, reagents and instruments may differ from published reference values. These reference values pave the way for the clinicians to apply these indices in the investigations of disease states.
Keywords: Normal, range, Platelet, volume, indices, Sudan.
Title: Reference Value of Platelets Count and Indices in Sudanese Using Sysmex KX-21
Author: Awad-Elkareem Abass, Israa Ismail, RazazYahia, Eman Ali, Reem Mohammed, Sara Mohammed, Haifa Alamin, Adam Ali
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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