Abstract: The aim of this study was to investigate the role of extended lymph node dissection in patients with gastric cancer undergoing surgical treatment for GC. The present review was also to evaluate the outcomes of lymphadenectomy in GC patients. We performed comprehensive search including; reviews, RCT, systematic reviews, and case reports using electronic databases such; CENTRAL, MEDLINE and Embase. We restricted our search to only English articles discussing the roles of lymph nodes resection during gastrectomy in case of gastric cancer that published up to April, 2017 with only human subject included. The results of this evaluation showed that D2 as well as D3 lymphadenectomy for gastric cancer could not demonstrate advantages in postoperative survival. Additionally, D3 lymphadenectomy could increase the risk of operative or postoperative problems. Nevertheless, the findings of this research could motivate the clinical area to re-think the inquiry of lymphadenectomy degree and also to perform a brand-new well-designed trial for gastric cancer surgical treatment. Less substantial lymphadenectomies likewise most likely result in increased loco-regional reappearance, and also could impact choices pertaining to adjuvant chemotherapy versus chemoradiation. In regards to overall survival, the impacts of even more considerable lymphadenectomy are tough to determine. In order to improve end results, the choice in between D1 versus D2 lymph node dissection need to be personalized after factor to consider of patient features, tumor phase as well as surgical experience, particularly since tummy cancers cells are now usually thoroughly treated by a multimodal technique consisting of perioperative radiation treatment or chemo-radiation.
Keywords: Lymphadenectomy, gastric cancer, surgical treatment.
Title: Roles of Lymphadenectomy in Gastric Cancer Surgery: Overview
Author: Naif Jazaa Aljohani, Yazeed Khaled A Binmahfouz, Ibrahim Abbas M Tai, Shaher Shakir Abdulrahim, Abdulrahman Mohammed Hamza
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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