Abstract: Medicinal plant Gymnema sylvestre (Asclepiadaceae) is a herb distributed throughout the world. The leaves showed antidiabetes, antimicrobial, antihypercholesterolemic, hepatoprotective and diuretic properties. Several active compounds such as, triterpenoid gymnemagenin, Gymnemic acid, Betaine, Beta-Carotene, Choline, Gymnemic-Acid, Niacin, Ascorbic-Acid have been reported from the leaves and root. In India leaves are mainly used as hepatoprotective and immunostimulatory agent, skin cosmetics and in the treatment of asthma, eye complaints, inflammations, snake bite, diabetes and obesity. G. sylvestre is a rare plant overexploited by traditional healers across the world. Therefore, endophytes can serve as the best alternate source for the host plant. Therefore, the present work was carried out to study the endophytic fungi of G. sylvestre and their role in the production of therapeutic active compounds. Present study was undertaken to evaluate the phytochemical constituents in the fungal endophyte VAG-4.The presence of Phenols, alkaloids, flavonoids, tannins, terpenoids and saponins were detected in both plant and fungal extracts. Among the phytochemicals detected in VAG-4, flavonoids (3.8%) were found to be maximum followed by phenols (2.1%), alkaloids (2.05%), saponins (1.08%), tannins (0.6%), terpenoids (2.8%). Similarly, the Plants reveals maximum of flavonoids (8.1%) followed by phenols (4.32%), alkaloids (3.75%), saponins (2.22%), tannins (1.2%) and terpenoids (5.8%). The fungal endophytes in isolation was found more efficient in producing secondary metabolites than its association with host plant.
Keywords: Gymnema sylvestre, Endophytic Fungi, Phytoconstituents, Secondary metabolites.
Title: Studies on Secondary Metaboloids From Potential Endophytic Fungi Isolated from Gymnema sylvestre R. Br
Author: AMBIKA VASANTAKUMAR, VIDYASAGAR G.M
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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