Abstract: The association between gastro-esophageal reflux disease (GORD) and chronic obstructive pulmonary disease (COPD) exacerbation has so far remained unclear.
AIMS AND OBJECTIVE: To Study the prevalence of GERD in COPD patients (in western part of UP).
To analyze the association of GERD and stage of COPD.
Methods: A total of 100 patients of diagnosed COPD as defined by GOLD guidelines were taken. Symptoms of GERD was evaluated by taking a proper history and the patients who were having the symptoms of heartburn and regurgitation were underwent for UGI endoscopy and graded accordingly.
Inclusion criteria was -Age >30 year, Stable COPD patients and Exclusion criteria was Respiratory disorder other than COPD, Known esophageal disease such as cancer, achalasia, stricture, Patient with ALD, CKD and ASCITES, Recent history of MI or STROKE, Acute cardio-respiratory failure. Statistical analysis was performed for categorical data and the independent t test for interval data.
RESULT: There are (54)% patients who have symptoms of GERD present and they underwent UGI endoscopy to look for presence of inflammation, erosions or ulcerations. Stage 1 COPD have 15 patients in which symptoms of GERD were absent and 1 had symptoms, which is of Grade A, and in Stage 2 COPD have 10 patients in which symptoms of GERD were present, out of which 9 were from Grade B and 1 from Grade A and in Stage 3 COPD have 9 patients in which symptoms of GERD were absent and 43 had symptoms, out of which 5 were from Grade-A 24 were from Grade B and 14 were from Grade C.
Conclusion: Reveals much high association between the COPD and GERD, and more the stage of COPD higher the chance of GERD.
Keywords: COPD Patients, gastro-esophageal reflux disease GERD.
Title: Study of Gastro Esophageal Reflux Disease in COPD Patients
Author: Dr. P. K. Gupta, Dr. Vinod Kumar Tyagi, Dr. Mohit, Dr. S.K. Virmani, Dr. Abhishek Gupta
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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