Study of Lipid Profile in Relation with Hypothyroidism

GULAB KANWAR, KUSUM BALA JAIN, JITENDRA JAIN

Abstract: Thyroid gland plays an important and specific role in the endocrine system. Hypothyroidism is one of the most common disorders seen in present days especially among women. Thyroid hormones have significant effects on synthesis, mobilization and metabolism of lipids. So this study was conducted to find out the association of lipid profile with hypothyroidism. MATERIAL AND METHOD: This study was conducted in Department of Biochemistry, GMC kota.50 patient samples and 50 control samples were taken. Serum was separated and serum lipid profile levels were estimated by fully Automated Analyzer ERBA EM 360.Thyroid estimation was done on Roche Chemiluminescence Analyzer. Data was analyzed using Mann- Whitney U test. RESULT: Cases have significantly higher values for serum lipid profile than controls and have significant positive correlation with TSH.  CONCLUSION:  Our data statisticaly suggest that hyperlipidemia is associated with hypothyroidism.  These enhance the risk for development of atherosclerosis and coronary artery disease.

Keywords: Hypothyroidism, Cholesterol, Triglycerides, V LDL, LDL, HDL.

Title: Study of Lipid Profile in Relation with Hypothyroidism

Author: GULAB KANWAR, KUSUM BALA JAIN, JITENDRA JAIN

International Journal of Healthcare Sciences

ISSN 2348-5728 (Online)

Research Publish Journals

Vol. 3, Issue 2, October 2015 – March 2016

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Study of Lipid Profile in Relation with Hypothyroidism by GULAB KANWAR, KUSUM BALA JAIN, JITENDRA JAIN