Abstract: Preventive and therapeutic activity of green tea is well known, the reports pertaining to the synergetic effect of its constituent polyphenolic catechins are of current interest to many, such as chemists, biologists, scientists from pharma industry, naturopathy, etc. Present report describes the results from an experimental investigation about the effect of two metal ions - Al(III) and Fe(II) on binding affinity of two catechin compounds, (–)-epigallocatechin (EGC) and (–)-epigallocatechin gallate (EGCG) with bovine serum albumin (BSA) and calf thymus 2- deoxyribonucleic acid(CT-DNA) using UV-visible spectroscopic method. Calculated Binding constant values indicate that the interaction of EGCG and EGC with BSA increases significantly for each metal-catechin conjugates.
Keywords: Green tea catechins, EGCG, EGC, BSA, Binding constant, UV-titration.
Title: Synergetic Effect of Green Tea Catechins in Presence of Metal Ions
Author: Seema Verma, Prateek Pandya, Neelima Gupta
International Journal of Interdisciplinary Research and Innovations
ISSN 2348-1218 (print), ISSN 2348-1226 (online)
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