Abstract: Severe lymphoblastic leukemia (ALL) accounts for over 75% of childhood leukaemias and is the most common childhood cancer. It is a complicated malignant disease that affects haematopoietic cells of the bone marrow and is epitomized by the malignant proliferation of lymphoblasts that impact the normal process of maturation and distinction of cells in the bone marrow, resulting in the replacement of regular bone marrow tissue with malignant cells .He aim of this paper is to systematically review studies on QOL in children during treatment for ALL with consideration to methodological details and quality of studies, empirical findings on QOL as reported by children and parents, and whether children and parents differ in their reports on QOL. Searches were conducted in biomedical, psychological and behavioral science databases. Six papers met inclusion criteria for review: 4 cross-sectional studies and 2 qualitative studies. This review reports on QOL research on kids with ALL drawing on quantitative and qualitative research studies performed in between 2001 and 2007. Efforts at advancing the study of QOL in kids on treatment for ALL were kept in mind, as obvious in a longitudinal research study style in 1 study, qualitative research in 2 research studies, direct access to children's reports on QOL in 3 research studies, and a shift to using disease particular QOL measures. The studies illustrate the prospective to continue advancing the methodology of QOL research study on kids with ALL. The knowledge obtained from future research, particularly empirical data, could supply beneficial details for professionals when resolving QOL care with children on retardment for ALL. This evaluation is based on a little number of studies, it offers a basis for upgrading over time as brand-new studies are published.
Keywords: QOL, Severe lymphoblastic leukemia (ALL).
Title: Systematic Review of Pediatrics Acute Lymphoblastic Leukemia
Author: Abdullah Dial A Alshamrani, Shahd Sameer Majdali, Shahad Abdulbasit A Alhutami, Fatimah Abdullah R Al Herz, Mohammad Fawzi H Qusty, Ali Hashem M Alzahrani
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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