Systematic Review of Pneumococcal Vaccination of Preterm Infant

Fayez Sulobi Alenezi, Mohana Jabban Alenezi, Fahad Ali AlZahrani, Osama Saleh Alnefisah, Abdullah Sulaiman Alturaif, Abdulmajeed Mousa Saud Al Harbi, Abdulaziz Abdullah Aldalbahi, Suhail Mohammed Alzahrani

Abstract: Streptococcus pneumoniae is among the major bacterial pathogens responsible for a wide spectrum of invasive disease and severe breathing system infections such as community-acquired pneumonia, intense otitis media, bacteremia, and meningitis, specifically in children younger than 2 years in both developing and industrialized countries. Therefore, the goal of this systematic review study was to evaluate the Pneumococcal Vaccination of Preterm Infant from different perspectives, including benefits, mortality, efficiency side effects, and international programme for this type of vaccinations. Articles were identified from systematic searches of the PubMed (MIDLINE), Embase and Cochrane Collaboration databases, through the period up to December 2016, Our search included reviews of bibliographic reference lists of identified studies. The literature search covered all years and there was language restriction to English, and only articles with Human subjects, thus animal’s models were excluded in this review. PCV13 was well endured in early infants. Different priming schedules resulted in higher IgG concentrations at various times throughout the very first 13 months of life. We believe that such information will be beneficial to those planning or providing pneumococcal vaccines to preterm infants and will allow them to think about this finding in the context of their own immunization programs and epidemiologic circumstance, in other studies PCV-7 immunogenicity among VLBW infants, even the tiniest and least mature infants normally accomplished antibody concentrations much like those explained in full-term infants. The favorable immunogenicity of PCV-7 amongst. Keywords: Pneumococcal Vaccination, Preterm Infant, VLBW. Title: Systematic Review of Pneumococcal Vaccination of Preterm Infant Author: Fayez Sulobi Alenezi, Mohana Jabban Alenezi, Fahad Ali AlZahrani, Osama Saleh Alnefisah, Abdullah Sulaiman Alturaif, Abdulmajeed Mousa Saud Al Harbi, Abdulaziz Abdullah Aldalbahi, Suhail Mohammed Alzahrani International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Vol. 4, Issue 2, October 2016 – March 2017

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Systematic Review of Pneumococcal Vaccination of Preterm Infant by Fayez Sulobi Alenezi, Mohana Jabban Alenezi, Fahad Ali AlZahrani, Osama Saleh Alnefisah, Abdullah Sulaiman Alturaif, Abdulmajeed Mousa Saud Al Harbi, Abdulaziz Abdullah Aldalbahi, Suhail Mohammed Alzahrani