Abstract: Gout is a disease of urate metabolism where an excess of serum uric acid leads to the formation of monosodium urate crystals in various tissues of the body and presents with chronic inflammatory joint condition, urate nephropathy, and/or tophi deposits. this study was aimed to investigate and evaluate the validity of diagnosis of Gout by family physicians, through a review of evidence based that discussed many different approaches such synovia fluid analysis, MSU crystals as the reference test or by the signs and symptoms of patients. We conducted a systematic search of different database, PubMed and Cochrane Central Register of Controlled Trials (CENTRAL) from the 1970s to the 2016 to find articles on gout diagnosis and management in family practice. We used a search strategy based on the Cochrane Highly Sensitive Search Strategy for identifying all kind of studies including randomized trials, systematic reviews, Cohort, and case reportsAcute gout manifests as severe joint pain, of rapid onset, reaching maximal intensity within a few hours. Gout has a predilection for lower extremity joints. The joint affected is usually hot, red, swollen and very painful. This is often associated with skin erythema. Identification of MSU crystals in the synovial fluid of an inflamed joint or from tophi allows a definite diagnosis of gout to be made.
Keywords: MSU crystals, PubMed and Cochrane, Central Register of Controlled Trials (CENTRAL).
Title: Systematic Review of Recognition Possibilities and Management of Gout in Primary Care
Author: Abeer Ahmed Sharahili, Yusra Saad Alruwaili, Maryam Mohammed ALkhaldi, Waad Hamoud Alenazi, Iman Nazal Alanazi, Ohoud Salman Alenazi
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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