Abstract: Cytomegalovirus (CMV)is a common pathogen in the general population with reported seroprevelance of 40-100% in general population. Primary infection in immune competent people is usually asymptomatic or results in infectious mononucleosis syndrome. However; it is a major cause of morbidity and mortality in patients with Acquired Immunodeficiency Syndrome (AIDS). It can result in retinitis, esophagitis, colitis, pneumonia, and central nervous system disease.This usually results from reactivation of primary infection. With the advent of effective antiretroviral treatment (ART), there has been a dramatic decline in the occurrence of CMV disease in AIDS patients.
This is a case report of a 36 years old lady who was admitted to the hospital with convulsions. She was found to be HIV positive. During the course of her hospital stay, she developed bloody diarrhea. The patient was suspected to have systemic CMV infection when CMV was detected in the blood, endotracheal secretion and the cerebrospinal fluid (CSF). Valgancyclovir was started in combination with intravenous immunoglobulin (IVIG).This resulted in a significant improvement of the patient’s condition. Early initiation of Anti-retroviral treatment (ART) was avoided to prevent the development of immune reconstitution syndrome.
Keywords: Acquired Immunodeficiency Syndrome (AIDS), CMV disease.
Title: Systemic CMV Infection in Acquired Immunodeficiency Syndrome (AIDS) Patient: A Case Report
Author: Ebaa Al-Awadhi, Mamoun Al-Qaseer
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
Research Publish Journals
