T- Cell Transfer as an Effective Cancer Immunotherapy: Systematic Review

Abstract: Significant effort has been extended over the past few years to evaluate the potential for adoptive T cell transfer to treat cancer. We aimed with this Systematic review study to evaluate the effectiveness of T cell transfer for cancer immunotherapy, also aimed to discuss the different approaches using this immunomodulation of T cell, and to overview those successful trails that have performed this method of treatment. Databases, PubMed, EMBASE, were searched to identified relevant trails discussing the effectiveness of T cell transfer for cancer immunotherapy; we searched for eligible studies that were published in English languages up to December 2016. Adoptive T cell transfer for cancer and chronic infection is an emerging field that shows promise in recent trials. Artificial biology-based engineering of T lymphocytes to reveal high affinity antigen-receptors can conquer immune tolerance, which has been a major restriction of immunotherapy-based techniques. Keywords: T cell transfer, Databases, PubMed, EMBASE. Title: T- Cell Transfer as an Effective Cancer Immunotherapy: Systematic Review Author: Sami Marei Ali Alqahtani, Mohammed Awn Dhafer Alqahtani, Jaber Ibrahim Jaber Assiri, Albara Abdullah mohammad Al mushham, Saleh Saeed Ali Alqarni, Hatim Abdullah Hossain Ramza, Khalid Hussain Mohammed Alhassani, Assaf Abdullah Assaf Alkatheri International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

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