Abstract: Premature rupture of membranes is considered one of the most important common obstetric complications as it corresponds to about 3.7-17% of pregnancies according to Wilson, as well as 5-45% according to Johnson Etal.
Appropriate management once diagnosed is essential. Hospitalization is mandatory as PROM is one of the predisposing factors of puerperal sepsis therefore, it is considered a high risk condition, threatening the life of the mother and the fetus. Thus, pregnancy should be terminated once amniotic sepsis has developed. (Fernando)
Most obstetricians tend to just wait and monitor their patients, for at least 24 hours as spontaneous labor is expected in such period before labor induction and acceleration, according to (Ekman & William). Some conventional labor induction methods are used, like oxytocin induction, which causes hyperbilirubinemia, one of its most important complications especially in preterm infants.
While, the other problem facing oxytocin induction is the presence of unripe cervix which does not respond to oxytocin induction, causing the termination of pregnancy to fail.
Hence, it is ought to develop another method to ripen the cervix more and increase the sensitivity of the inner and outer oxytocin receptors.
Abbreviations: PROM = Premature Rupture of Membranes.
Keywords: PROM – Pregnancy termination – Prostaglandins – Labor induction.
Title: Termination of Pregnancy in PROM Using Prostaglandins
Author: Dr. Zakwan KHRAIT
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
Research Publish Journals
