Abstract: One of the main contributing factor to skin aging is oxdative stress. Previous studies showed that antioxidants are necessary for inhibiting the process of skin aging due to oxidative stress through antioxidant properties and inflammation inhibition. Duwet (Syzgium Cumini) which is planted in Indonesia is know to have high concentration of antioxidant. The aim of this study to assess Duwet ethanol extract cream effects on number of Langerhans cell on the dorsal skin of male Wistar rats exposed to UV-B. This study is purely experimental research. A post-test only control group design research was conducted on 30 male rats. Group were divided into control (P1), placebo (P2), 5% (P3) , 10% (P4) and 20% (P5) Duwet ethanol extract concentrations. The control, placebo, 5%, 10% and 20% shows significant result to (p>0.05). The mean difference of P1, P2, P3, P4 and P5 was 26.00, 50.00, 48.0, 52.67 and 58.00. This study show that Duwet ethanol extract cream can preserve the number of Langerhans cell.
Keywords: Number of Langerhans Cell, Duwet, UV-B, Antioxidant.
Title: The Effect Of Duwet Extract (Syzygium Cumini) On Langerhans Cells As Result Of Ultraviolet B Exposure On The Dorsal Skin Of Male Wistar Rat
Author: Nur Aisyah Farhanah Abd Jalil, IG Nyoman Sri Wiryawan, IGA Dewi Ratnayanti
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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