Abstract: Exposure to UV-B rays is one of the causes of premature skin aging known as photoaging. Many sources state that the use of antioxidants can reduce the effects of aging caused by UV-B exposure. This research aims to study the effect of using garlic extract, which is rich in antioxidants, on the thickness of the skin of wistar rats that exposed to UV-B rays. This study used 30 male wistar rat samples weighing 150-200 grams, extending 3-4 months. The sample grouping is done randomly and divided into 6 different groups which are K1 (control group), K2 (cream based), K3 (sunblock), K4 (5% extract single garlic cream), K5 (10% extract single garlic cream), and K6 (20% extract single garlic cream) , where irradiation is given for 3x every week with the same total dose of 840 mJ/cm2. The results showed a big difference between each group with means of K1 (966.182 μm), K2 (894.03 μm), K3 (900.16 μm), K4 (826.36 μm), K5 (784.12 μm), and K6 (757.83 μm). This shows that the administration of a single garlic cream extract (Allium sativum) is able to prevent thickening of the dermis of wistar rats that exposed to UV-B rays.
Keywords: photoaging, garlic extract, dermis thickness, UV-B light.
Title: THE EFFECT OF SINGLE GARLIC EXTRACT (ALLIUM SATIVUM) CREAM TO THE THICKNESS OF DERMIS OF THE MALE WISTAR RATS (RATTUS NORVEGICUS) SKIN THAT EXPOSED WITH RAY ULTRAVIOLET-B
Author: Ester Priskila Sabatini, I Gusti Ayu Dewi Ratnayanti, I Gusti Kamasan Arijana, Ni Made Linawati
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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