Abstract: The risk factor is described as something that develops the risk of breast cancer. A woman can develop breast cancer due to the various causes. It can be affected by behavior, substance or environmental condition. The purpose of this systematic review is to determine the risk factors of breast cancer. The method of writing this article is systematic review, where the articles were published from 2015 to 2020 that focused on assessing the risk factors of breast cancer. Assessment of the methodological quality of each article was carried out using PRISMA checklist. The results of the analysis of breast cancer risk factors in women are age (p value = 0.0001), family history (p value = 0.0001), age at menarche (p value = 0.036), age at menopause (p value = 0.05), age at first full term pregnancy (p value = 0.033), menopausal status (p value = 0.001), parity (p value = 0.001), breastfeeding (p value = 0.028), oral contraceptive (p value = 0.03), BMI (p value = 0.0001), active smoker (p value = 0.051), and alcohol intake (p value = 0.001). Based on the review conducted, there is a strong correlation between age, family history, age at menarche, age at menopause, age at first full term pregnancy, parity, usage of oral contraceptive, body mass index and alcohol that are very much associated as risk factors of breast cancer. However, smoking has no significant correlation to breast cancer.
Keywords: Women, Breast Cancer, Risk Factors.
Title: THE RISK FACTORS OF BREAST CANCER: A SYSTEMATIC REVIEW AND META-ANALYSIS
Author: Nanthini Siva Kumar, Putu Anda Tusta Adiputra, I Wayan Sudarsa, I Gede Budhi Setiawan
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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