Abstract: The midgut gland of the rusty millipede, Trigoniulus corallinus contains lectin specific for Gal β1-3 linkage and N-acetyl sialic acid. Biological role of the midgut gland lectin (TcLec) of the rusty millipede, T. corallinus was studied based on induction and clearance analysis, using erythrocytes of diverse origin as pathogen model. All the erythrocytes when injected into the hemocoel, inspite of their agglutinability and concentration revealed enhanced production of lectin following an initial reduction in HA titre in all the tested tissues except hemolymph. Experiments on clearance of the injected lectin coated and uncoated erythrocytes of diverse agglutinability into the hemocoel showed a positive correlation between the extent of the agglutination and lectin coating on in vivo clearance. Hemolysis of the injected erythrocytes in vitro revealed that hemocytes recognize and lyse the lectin coated erythrocytes much faster than the uncoated erythrocytes confirming that the lectin act as an ‘opsonin’ which is a prerequisite for hemocyte mediated lysis and clearance.
Keywords: Agglutination, Erythrocytes, Induction, Clearance, Midgut gland, Opsonin, Lectin.
Title: THE SELF-PROTECTIVE ROLE OF THE MIDGUT GLAND LECTIN (TcLec) IN THE RUSTY MILLIPEDE, T. CORALLINUS
Author: Anitha C, Basil Rose M.R, Arokya Glory P.T
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
Research Publish Journals
