Abstract: Infection with Herpes Simplex Virus Type-2 (HSV-2) is the primary cause of genital herpes and the most common cause of genital ulcer disease (GUD) worldwide. The aim of this study is to assess the seroprevalence of HSV-2 infections among HIV infected adults attending antiretroviral clinic in Specialist Hospital Sokoto; and to verify the association between HSV-2 infection and HIV-status, age, level of education and positive history of painful genital ulcers. Specimens (blood sample) were collected from one hundred (100 )volunteers attending Antiretroviral Clinic in Specialist Hospital Sokoto and tested for HSV-2 antibodies using a one-step cassette style HSV-II IgG which work based on the principle of immunoassay combined with conjugated colloid gold technology. Data were analyzed using SPSS version 18.0. P values ≤ 0.05 were considered significant. Out of the 100 individuals tested, 17 (17.0%) were HSV-2 positive. Infected individuals were more likely to be female than male (12% versus 5%; P > 0.05). There were high rates of infection in all age groups, and the prevalence increased with age. However, multivariate logistic regression analysis showed that HSV-2 prevalence was significantly associated with occupation, educational status, and number of sex partners and sexual behaviors (P > 0.05) and not significant with age, marital status, tribe, religion, p>0.05.The results highlight the potential public health impact of HSV-2 in Nigeria where anti-HSV-2 testing is not generally done in all populations.
Keywords: Herpes Simplex Virus, HIV, HSV-2, Specialist Hospital Sokoto.
Title: The Seroprevalence of Herpes Simplex Virus2 among HIV infected adults attending antiretroviral clinic in Specialist Hospital Sokoto, Nigeria
Author: Saidu, A.Y., Munir G., Mustapha U. K., Abubakar B. U.
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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