Abstract: Osteomyelitis is inflammation of bone and bone marrow caused by the many pathogenic agents especially S. aureus originated by many etiologies e.g., trauma. Osteomyelitis is diagnosed by clinical signs and symptoms, laboratory tests, imaging analysis, histological studies, and microbiological studies and at the end identification of pathogen through blood culture. Treatment of osteomyelitis includes antimicrobial therapy and debridement of dead tissue. Combination of oral and parenteral antibiotics used in antimicrobial therapy to treat osteomyelitis. Surgical method involves when antibiotic therapy fails to treat the disease. Muscle flap and hyperbaric oxygen therapy is also used for the management of osteomyelitis. Recently maggot therapy is used to remove the dead tissue from the infected site; it is cost effective and rapid debridement method. Due to resistance to antibiotics, management of osteomyelitis is ultimate challenge for clinicians. Morbidity of osteomyelitis can be reduced through diagnosis and initiation of appropriate treatment at time.
Keywords: Bone-marrow, S. aureus, osteomyelitis, antibiotics, maggot-therapy.
Title: Therapeutic Considerations of Osteomyelitis: A review
Author: Talhat Munir, Dr.Razia Iqbal, Sana Naseem, Tamkeen Zainab, Muhammad Hashim
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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