Utilization of Platelet Concentrates in Patients with Thrombocytopenia – A Hospital Based Study

Dr. Supriya Pradhan, Dr. Vijay Dombale, Dr. Prabhu MH, Dr. Shivanand Gundalli

Abstract: Platelet transfusion is an effective therapy for the prevention and treatment of bleeding. The aim of the study was to determine the number of platelet transfusions that was done during the study period, to study the indications for the transfusions and evaluate its efficacy. 140 thrombocytopenic patients who received platelet transfusions were evaluated during a one-year study period. Conditions associated with the thrombocytopenia were studied and categorized. Pre and post-transfusion platelet counts were done and 24-hour corrected count increment (CCI) was calculated to check the efficacy of transfusion.Majority of the platelet recipients were transfused prophylactically when their platelet counts were >20000/μL. The most common category of diagnosis among these patients was infectious diseases. 46% of patients showed significant 24-hour CCI. The rest of patients showed no significant increment in their platelet counts after transfusion. Appropriate component therapy should be actively endorsed as it ensures optimum utilization of a scarce resource in a populous third world country like India. A Hospital Transfusion Committee would seem to be a good start to monitoring transfusion practices and steering them in the correct direction.

Keywords: Thrombocytopenia; platelet transfusion; platelet concentrate, corrected count increment.

Title: Utilization of Platelet Concentrates in Patients with Thrombocytopenia – A Hospital Based Study

Author: Dr. Supriya Pradhan, Dr. Vijay Dombale, Dr. Prabhu MH, Dr. Shivanand Gundalli

International Journal of Healthcare Sciences

ISSN 2348-5728 (Online)

Research Publish Journals

Vol. 3, Issue 1, April 2015 - September 2015

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Utilization of Platelet Concentrates in Patients with Thrombocytopenia – A Hospital Based Study by Dr. Supriya Pradhan, Dr. Vijay Dombale, Dr. Prabhu MH, Dr. Shivanand Gundalli