Abstract: The latest Ebola virus disease outbreak in West Africa caused over ten thousand deaths. Due to its high fatality rate, patients have only about ten to fifty percent survival rate. According to World Health Organization (WHO), there is no approved drug for Ebola virus disease yet. Thus the need to find the curing drug for Ebola virus disease still persists. Natural products are invaluable in term of drug development. Thus in this study, natural products from ZINC database were used for virtual screening against Ebola virus glycoprotein responsible for the virus infectivity. Result analysis shows that a natural product could potentially inhibit Ebola virus glycoprotein inhibitor.
Keywords: Ebola virus, natural products, glycoprotein.
Title: Virtual Screening for Natural Products with Potential Inhibitory Effect on Ebola Virus Glycoprotein
Author: Rungsang Nakrumpai
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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