Abstract: Background: There are several factors that seem to play a role in diabetes development including genetic, lifestyle, environmental and nutritional conditions. Amongst nutritional factors, vitamin D is likely to have an important role either in glycemic control or in attenuating diabetic complications. The probable mechanisms indicating the role of vitamin D in glucose homeostasis is likely to be through beta cell dysfunction and insulin resistance in cases with vitamin D deficiency. Objectives: the aim of this study was to determine the correlation between HbA1c and 25(OH) D and the involving of diabetic and non diabetic patients in these changes. This paper is attends to investigate the effect of Vitamin D on Glycated Hemoglobin (HbA1c) level. Method: We performed cross-sectional study that examined the effect of vitamin D on Glycated Hemoglobin (HbA1c) level in 184 Adult participants from diabetic and non diabetic patients attending King Fahad hospital in Jeddah during the years 2015. The average age was 42 years. The relation between diabetic and non diabetic patients effected by Vitamin D on Glycated Hemoglobin (HbA1c) level was modeled by statistical SPSS multiple linear regression analyses. Results: the rate of Vitamin D Deficiency among patients included in this study a very high percentage which is 82% of them have Deficiency amount of Vitamin D in this body which meant that they are under big risk of getting diabetes type 2. And the other shocking result is that only 2.2% which means 4 patients out of 184 having sufficient amount of Vitamin D, sadly this shows that our population is under risk of other skeletal disorders than diabetes. Conclusion: accumulating the evidence from several studies, vitamin D is likely to have a role in Diabetic and non diabetic patients and Hb-glycation. However, the relationship between serum 25OHD with hemoglobin glycation (HbA1c) and insulin resistance in Diabetes has not been extensively studied before, but we could not see any correlation in our study.
Keywords: vitamin D, glucose homeostasis, non diabetic, Glycated Hemoglobin (HbA1c), Diabetic.
Title: Vitamin D Effects on Glycated Hemoglobin (Hba1c) Level, And Their Correlation between Diabetic and Non Diabetic in Adults
Author: Ahlam albisaisi, Daniyah baduqayl, Esraa gadah, Hamza halawani
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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